肝素IIa檢測試劑盒221025
北京市肝素檢測試劑盒廠家
價格： 電議
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手機： 15811483643 郵箱： 2850669801@qq.com
傳真： 010-64814276 地址： 北京市 北京市
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| 品牌： | HYPHEN BioMed |
| 保存條件： | 2-8度 |
| 供應商： | 優(yōu)尼康 |
| 數(shù)量： | 100盒 |
| 規(guī)格： | 2×5ml |
| 保質期： | 2年 |
| INTENDED USE: This Heparin Anti-IIa method is a two stage chromogenic assay for measuring the conceation of heparin, and heparin like anticoagulants, using an automatic or a manual method, for heparin conceation ranges from 0.002 to 0.04 IU/ml (*) in the tested dilution (or from 0 to 1 IU/ml in plasma tested diluted 1:25). This method can be used for testing heparin in human citrated plasma, or in purified solutions. TEST PRINCIPLE: The Heparin Anti-IIa method is a two stage chromogenic anti-IIa assay developed for measuring heparin (UFH), or heparin like anticoagulants, in human citrated plasma, or in purified solutions, for their Anti-IIa activity. Heparin is a sulphated polysaccharide with a high affinity for antithrombin. When complexed with heparin, antithrombin exhibits a fast acting and potent inhibitory activity for coagulant serine esterases: IXa, Xa and thrombin. LMWH, and heparin analogues, such as Sodium Danaparo?d, inhibit more efficiently Factor Xa than thrombin, whilst UFH inhibits efficiently thrombin and also the other serine esterases. Anti-IIa assays are then the right methods for measuring the anti-thrombin activity of large heparin molecules. The Heparin Anti-IIa method is a two stage method based on the inhibition of a constant amount of Thrombin (IIa), by the tested heparin in presence of exogenous antithrombin, then hydrolysis of a Thrombin specific chromogenic substrate, by Thrombin in excess. pNA is then released from the substrate. The amount of pNA released is then a relation of the residual Thrombin activity. There is an inverse relationship between the conceation of heparin and color development, measured at 405 nm. Heparin + AT ?[AT Hep.] [AT Hep.] + [IIa (excess)] ? [FIIa-AT-Hep.] + [residual FIIa] [FIIa (residual)] + IIa-Subs. ? Pep + pNA |
聯(lián)系人：王女士
TEL:15811483643
QQ: 2850669801
郵箱：2850669801@qq.com
￥36600
￥28975
電議
電議
北京優(yōu)尼康生物科技有限公司
注冊資金：100萬以下
聯(lián)系人：王小姐
固話：
移動手機：15811483643
企業(yè)地址：北京市 北京市
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