價(jià)格: 電議
物流: 湖北 武漢市| 賣(mài)家支付運(yùn)費(fèi)
可銷(xiāo)售總量: 99件
手機(jī): 18162422647 郵箱: nebio0923@163.com
傳真: 尚未完善 地址: 湖北 武漢市
[IDH1(R132H) IDH1小鼠單抗 IDH1鼠抗體]
郵箱:
手機(jī):
| 貨號(hào): 26081 |
| 基因符號(hào): IDH1 |
| 描述: Anti-IDH1(R132H) Mouse Monoclonal Antibody |
| 背景介紹: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors. |
| 原: Recombinant protein of human IDH1 which includes the mutation of R132H |
| 經(jīng)過(guò)測(cè)試的應(yīng)用: ELISA, WB, IHC, IF |
| 推薦稀釋比: ELISA: 1: 1000-1: 5000 WB: 1: 100-1: 1000 IF: 1: 50-1: 100 IHC: 1: 50-1: 100 |
| 濃度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亞型: IgG |
| 純度: Purified from ascites |
| 防腐劑: No |
| 成分: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol |
| 種屬反應(yīng)性: Anti-IDH1(R132H) antibody recognizes IDH1(R132H) of vertebrates |
| 儲(chǔ)存條件: Store at -20°C. oid repeated freezing and thawing |
| 蛋白質(zhì)印跡: Western blot analysis of recombinant IDH1(R132H) and wild-type proteins. Purified His-tagged IDH1(R132H) protein (Cat.#10199) and wild-type protein (amino acid 1-240) (Cat.#10198) were blotted with anti-IDH1(R132H) mouse antibody (Cat.# 26081)(Left panel) or with anti-IDH1 mouse antibody (Cat. #26136 right panel). 熒光: Immunofluorescence of cells expressing IDH1 proteins with anti-IDH1(R132H) antibody. HEK293T cells were transfected with pCDNA3-GFP-IDH1 (WT) plasmid (left column) or pCDNA3-GFP-IDH1(R132H) plasmid (right column), then fixed and stained with Anti-IDH1(R132H) monoclonal antibody (Cat. #26081). |
注冊(cè)資金:100萬(wàn)-500萬(wàn)
聯(lián)系人:付女士
固話(huà):027-63497286
移動(dòng)手機(jī):18162422647
企業(yè)地址:湖北 武漢市 東西湖區(qū)